Saturday, April 14, 2018

Where's the Beef?

Worldwide Patterns of Ancestry, Divergence, and Admixture in Domesticated Cattle
http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1004254

Bos taurus taurus was domesticated in the Middle East while Bos taurus indicus was domesticated in India. 

It is likely is that a hypothetical Punjab_N population from even before agriculture would have been related to the Iran_N people, somewhere along a cline between Iran_N in Iran (whose aDNA has been found) and peoples in India's interior. 

If Iran_N(eolithic) ingressed into India with a demic diffusion of agriculture, they didn't bring their cattle along. 

13 comments:

tim drake said...
This comment has been removed by the author.
tim drake said...

Regarding milk, there was a genetic study on a tribe called "Kalash" (who btw have the highest Steppe related ancestry among South Asian populations in the latest paper) in pakistan. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570283/ (n=23 samples were studied)
From the study -
"One striking example is the frequency of the derived allele for rs4988235, which has been linked to lactose tolerance. The Kalash, like the MA-1, are fixed for the ancestral allele
for this variant, whereas their neighbors in Pakistan have been observed to have moderate frequencies of the derived allele. Although this supports their long-term isolation, it is surprising in other ways because the Kalash have no reported lactose intolerance and indeed celebrate a "milk day" during their annual spring rituals.This suggests that there might be additional derived lactase-persistence alleles in the LCT-MCM6 (MIM: 601806) region in this
population."

Arun said...

There are at least 5 variants that are associated with lactase persistence.
http://answer2pakteahouse.blogspot.com/2018/04/lactase-persistence.html

tim drake said...
This comment has been removed by the author.
tim drake said...

"It is likely is that a hypothetical Punjab_N population from even before agriculture would have been related to the Iran_N people, somewhere along a cline between Iran_N in Iran (whose aDNA has been found) and peoples in India's interior" -- Already left a similar comment at another blog but in the admixture plot present in page 166 of the supplementary text of pre-print, the supposedly isolated Andamanese ONGE has a decent % (~25% to my naked eye) of Iran_N like ancestry (represented by teal color). How is this even possible if only the yellow component is supposed to be present in the ONGE ?

Arun said...

Excellent point!

Arun said...

But the supplementary material seems to have been updated?

tim drake said...

It's still there arun. Unlike the greater andamanese tribe , Onge were selected back in the Reich 2009 paper as they supposedly have remained unmixed and isolated (their mtDNA and Y-DNA haplogroups at least give that impression as their mtDNA and Y-DNA are not found in mainland), so how is possible to have Iran_N like admixture in them ?
What you say about Iran_N and punjab_N might be true ( Remember Dr Gyaneshwar said that there was a "dravidian" expansion towards north-west "which was so far not reported" about IVC prelims results ) !

tim drake said...
This comment has been removed by the author.
tim drake said...

Could you please cite the source where you found lactase persistence in Onge :)

tim drake said...

Sorry for being a bother but above ^^^^ question:P ?

Arun said...

Sorry, been busy.
"Of further curious note is the single Great Andamanese individual with a C/T genotype, suggestive of recent mainland Indian admixture"
https://academic.oup.com/mbe/article/29/1/249/1749245
Herders of Indian and European Cattle Share Their Predominant Allele for Lactase Persistence
Irene Gallego Romero Chandana Basu Mallick Anke Liebert Federica Crivellaro Gyaneshwer Chaubey Yuval Itan Mait Metspalu Muthukrishnan Eaaswarkhanth Ramasamy Pitchappan Richard Villems ... Show more
Molecular Biology and Evolution, Volume 29, Issue 1, 1 January 2012, Pages 249–260, https://doi.org/10.1093/molbev/msr190
Published:
11 August 2011


farheen s said...

Such a helpful post. Keep sharing post along these lines. I to a great degree favored your post. Take a gander at extra.
cruise services in andaman islands
Best sightseeing in andaman islands
Car rental hire services in andaman
Andaman tour packages